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Infection and Immunity

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CURRENT ISSUE
Volume 91Issue 1January 2023
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EDITOR IN CHIEF: Dr. Andreas J. Bäumler

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Editor in Chief

IAI EiC Baumler
Dr. Andreas J. Bäumler

Editor in Chief (2022) | University of California at Davis

Andreas J. Bäumler is Professor and Vice Chair of Research of the Department of Medical Microbiology and Immunology at the University of California at Davis. His laboratory studies the interaction between enteric pathogens, the host, and its gut microbiota. He is a highly-cited author noted by Clarivate in multiple years.

Editorial Board

Research ArticleInfection and ImmunityArticle
Sex Matters: Male Hamsters Are More Susceptible to Lethal Infection with Lower Doses of Pathogenic Leptospira than Female Hamsters
A somewhat contradictory published body of evidence suggests that sex impacts severity outcomes of human leptospirosis. In this study, we used an acute animal model of disease to analyze leptospirosis in male and female hamsters infected side by side with ...
MinireviewInfection and ImmunityArticle
Apoptosis, Pyroptosis, and Necrosis: Mechanistic Description of Dead and Dying Eukaryotic Cells
A wide variety of pathogenic microorganisms have been demonstrated to cause eukaryotic cell death, either as a consequence of infecting host cells or by producing toxic products. Pathogen-induced host cell death has been characterized as apoptosis in many of these systems. It is increasingly being recognized that cell death with some of the features of apoptosis may result from a variety of molecular pathways and that experimental techniques used to identify cell death often do not distinguish among these mechanisms. We propose that a clear understanding of the diversity of processes mediating cell death has been obscured by the simplicity of the nomenclature system commonly employed to describe eukaryotic cell death. This review presents a perspective on eukaryotic cell death and discusses experimental techniques used to study these processes.

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