1 May 1997

Efficacies of ofloxacin, rifampin, and clindamycin in treatment of Staphylococcus aureus abscesses and correlation with results of an in vitro assay of intracellular bacterial killing

Abstract

We studied the efficacies of ofloxacin, rifampin, and clindamycin in a Staphylococcus aureus abscess model and seven antimicrobial regimens in an intracellular killing assay. Ofloxacin plus rifampin was the most effective regimen in the abscess model, and rifampin and ofloxacin were the most active regimens in the intracellular killing assay.

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Published In

cover image Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy
Volume 41Number 5May 1997
Pages: 1178 - 1181
PubMed: 9145896

History

Published online: 1 May 1997

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Contributors

Authors

D M Bamberger
University of Missouri-Kansas City School of Medicine, 64108-2792, USA.
B L Herndon
University of Missouri-Kansas City School of Medicine, 64108-2792, USA.
M Dew
University of Missouri-Kansas City School of Medicine, 64108-2792, USA.
R P Chern
University of Missouri-Kansas City School of Medicine, 64108-2792, USA.
H Mitchell
University of Missouri-Kansas City School of Medicine, 64108-2792, USA.
L E Summers
University of Missouri-Kansas City School of Medicine, 64108-2792, USA.
R F Marcus
University of Missouri-Kansas City School of Medicine, 64108-2792, USA.
S C Kim
University of Missouri-Kansas City School of Medicine, 64108-2792, USA.
P R Suvarna
University of Missouri-Kansas City School of Medicine, 64108-2792, USA.

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